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16-bit Microcontrollers - MCU

16-bit Microcontrollers are in stock with same-day shipping at Mouser from industry leading manufacturers. Mouser is an authorized distributor for many 16-bit microcontroller manufacturers including Infineon, Microchip, NXP, STMicroelectronics, Texas Instruments & more. Please view our large selection of 16-bit microcontrollers below.

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Image	Part #	Mfr.	Description	Datasheet	Availability	Pricing (USD) Filter the results in the table by unit price based on your quantity.	Qty.	Core	Program Memory Size	Data RAM Size	Package / Case	Maximum Clock Frequency	ADC Resolution	Number of I/Os	Supply Voltage - Min	Supply Voltage - Max	Mounting Style	Data Bus Width	Minimum Operating Temperature	Maximum Operating Temperature	Series	Qualification	Packaging
16-bit Microcontrollers - MCU 16-bit MCU, S12 core, 32KB Flash, 32MHz, -40/+85degC, Automotive Qualified, QFP 64 S9S12HY32J0CLH NXP Semiconductors 1: $13.17 800In Stock	Mfr. Part # S9S12HY32J0CLH Mouser Part # 841-S9S12HY32J0CLH	NXP Semiconductors	16-bit Microcontrollers - MCU 16-bit MCU, S12 core, 32KB Flash, 32MHz, -40/+85degC, Automotive Qualified, QFP 64	Datasheet	800In Stock	$13.17 $10.00 $9.59 $8.45 View $8.03 $7.77 $6.71	Min.: 1 Mult.: 1	S12	32 kB	2 kB	QFP-64	64 MHz	10 bit	50 I/O	4.5 V	5.5 V	SMD/SMT	16 bit	- 40 C	+ 85 C	S12HY	AEC-Q100	Tray
16-bit Microcontrollers - MCU 16-bit MCU, S12 core, 32KB Flash, 32MHz, -40/+125degC, Automotive Qualified, QFP 64 S9S12P32J0MLH NXP Semiconductors 1: $9.28 1,600In Stock	Mfr. Part # S9S12P32J0MLH Mouser Part # 841-S9S12P32J0MLH	NXP Semiconductors	16-bit Microcontrollers - MCU 16-bit MCU, S12 core, 32KB Flash, 32MHz, -40/+125degC, Automotive Qualified, QFP 64	Datasheet	1,600In Stock	$9.28 $7.22 $6.39 $6.13 View $5.70 $5.30 Quote	Min.: 1 Mult.: 1	HCS12	32 kB	2 kB	LQFP-64	32 MHz	12 bit	49 I/O	3.15 V	5.5 V	SMD/SMT	16 bit	- 40 C	+ 125 C	S12P	AEC-Q100	Tray
16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G13 128K 30LSSOP -40 to 85 C R5F100AGASP#10 Renesas Electronics 1: $5.30 1,680In Stock 3,360Expected 12/21/2026	Mfr. Part # R5F100AGASP#10 Mouser Part # 968-R5F100AGASP#10	Renesas Electronics	16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G13 128K 30LSSOP -40 to 85 C Learn More about Renesas Electronics renesas rl78 mcu	Datasheet	1,680In Stock 3,360Expected 12/21/2026	$5.30 $3.60 $3.28 $2.79 View $2.50 $2.29 $1.90 $1.89	Min.: 1 Mult.: 1	RL78	128 kB	12 kB	LSSOP-30	32 MHz	8 bit/10 bit	26 I/O	1.6 V	5.5 V	SMD/SMT	16 bit	- 40 C	+ 85 C	RL78/G13		Tray
16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G13 512K 64LFQFP -40 to 85 C R5F101LLAFB#10 Renesas Electronics 1: $6.26 1,280In Stock	Mfr. Part # R5F101LLAFB#10 Mouser Part # 968-R5F101LLAFB#10	Renesas Electronics	16-bit Microcontrollers - MCU 16-BIT GENERAL MCU RL78/G13 512K 64LFQFP -40 to 85 C Learn More about Renesas Electronics renesas rl78 mcu	Datasheet	1,280In Stock	$6.26 $4.31 $4.01 $3.53 View $3.35 $3.01 $2.58 $2.51	Min.: 1 Mult.: 1	RL78	512 kB	32 kB	LFQFP-64	32 MHz	8 bit/10 bit	58 I/O	1.6 V	5.5 V	SMD/SMT	16 bit	- 40 C	+ 85 C	RL78/G13		Tray
16-bit Microcontrollers - MCU 16BIT MCU RL78/L13 32K 64LFQFP -40/+85C R5F10WLCAFB#10 Renesas Electronics 1: $2.31 1,270In Stock	Mfr. Part # R5F10WLCAFB#10 Mouser Part # 968-R5F10WLCAFB#10	Renesas Electronics	16-bit Microcontrollers - MCU 16BIT MCU RL78/L13 32K 64LFQFP -40/+85C Learn More about Renesas Electronics renesas rl78 mcu	Datasheet	1,270In Stock	$2.31 $1.72 $1.63 $1.40 View $1.35 $1.29 $1.27 $1.26	Min.: 1 Mult.: 1	RL78	32 kB	1.5 kB		24 MHz	8 bit/10 bit	49 I/O	1.6 V	5.5 V	SMD/SMT	16 bit	- 40 C	+ 85 C	RL78/L13		Tray
16-bit Microcontrollers - MCU MCU 3/5V 96K Pb-free 64-QFP M30281FAHP#U9B Renesas Electronics 1: $27.46 68In Stock NRND	Mfr. Part # M30281FAHP#U9B Mouser Part # 968-M30281FAHP#U9B NRND	Renesas Electronics	16-bit Microcontrollers - MCU MCU 3/5V 96K Pb-free 64-QFP	Datasheet	68In Stock	$27.46 $23.42 $21.13 $19.72 View $19.42 $19.38 Quote	Min.: 1 Mult.: 1	M16C/60	96 kB	8 kB	LQFP-64	20 MHz	10 bit	55 I/O	2.7 V	5.5 V	SMD/SMT	16 bit	- 20 C	+ 85 C	M16C/28		Tray
16-bit Microcontrollers - MCU M16C65 768+24KB 2.7/5.5V -40/85C 128QFP R5F3651TDFC#U0 Renesas Electronics 1: $39.81 61In Stock NRND	Mfr. Part # R5F3651TDFC#U0 Mouser Part # 968-R5F3651TDFC#U0 NRND	Renesas Electronics	16-bit Microcontrollers - MCU M16C65 768+24KB 2.7/5.5V -40/85C 128QFP	Datasheet	61In Stock	$39.81 $33.53 $28.46 $28.08 View $27.88 Quote	Min.: 1 Mult.: 1														M16C/65		Tray
16-bit Microcontrollers - MCU 16B 256KB FL 32KBR 60MHz 44P OpAmps PIC24EP256MC204-E/PT Microchip Technology 1: $4.99 310In Stock	Mfr. Part # PIC24EP256MC204-E/PT Mouser Part # 579-PIC24256MC204EPT	Microchip Technology	16-bit Microcontrollers - MCU 16B 256KB FL 32KBR 60MHz 44P OpAmps Learn More about Microchip Technology microchip dspic33e dscs pic24e mcus	Datasheet	310In Stock	$4.99 $4.58 $4.13	Min.: 1 Mult.: 1	PIC24E	256 kB	32 kB	TQFP-44	60 MHz	10 bit, 12 bit	35 I/O	3 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 125 C	PIC24EPxxxMC20x	AEC-Q100	Tray
16-bit Microcontrollers - MCU 8KB Flsh 1KB RAM512B EEPROM 16MIPS I/O16 PIC24F08KA102-I/ML Microchip Technology 1: $3.07 298In Stock	Mfr. Part # PIC24F08KA102-I/ML Mouser Part # 579-PIC24F08KA102IML	Microchip Technology	16-bit Microcontrollers - MCU 8KB Flsh 1KB RAM512B EEPROM 16MIPS I/O16 Learn More about Microchip Technology microchipxlp	Datasheet	298In Stock	$3.07 $2.79 $2.55 $2.54	Min.: 1 Mult.: 1	PIC24F	8 kB	1.5 kB	QFN-28	32 MHz	10 bit	24 I/O	1.8 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	PIC24FxxKA10x	AEC-Q100	Tube
16-bit Microcontrollers - MCU MCU 3V 256K Pb-Free 144-QFP R4F24269NVFQV Renesas Electronics 1: $27.30 62In Stock NRND	Mfr. Part # R4F24269NVFQV Mouser Part # 968-R4F24269NVFQV NRND	Renesas Electronics	16-bit Microcontrollers - MCU MCU 3V 256K Pb-Free 144-QFP	Datasheet	62In Stock	$27.30 $21.36 $17.92 $17.91	Min.: 1 Mult.: 1	H8S/2600	256 kB	64 kB		33 MHz	10 bit	98 I/O	3 V	3.6 V	SMD/SMT	16 bit	- 20 C	+ 75 C	H8S/2400		Tray
16-bit Microcontrollers - MCU R8C24 64K+2K 52LQFP -20to85C R5F21248SNFP#V2 Renesas Electronics 1: $15.63 129In Stock NRND	Mfr. Part # R5F21248SNFP#V2 Mouser Part # 968-R5F21248SNFP#V2 NRND	Renesas Electronics	16-bit Microcontrollers - MCU R8C24 64K+2K 52LQFP -20to85C	Datasheet	129In Stock	$15.63 $11.87 $11.38 $9.58 $9.57	Min.: 1 Mult.: 1														R8C/24		Tray
16-bit Microcontrollers - MCU 16-bit 16MIPS 64KB Flash 8KB RAM PIC24FJ64GA102-I/SP Microchip Technology 1: $4.64 178In Stock	Mfr. Part # PIC24FJ64GA102-I/SP Mouser Part # 579-P24FJ64GA102ISP	Microchip Technology	16-bit Microcontrollers - MCU 16-bit 16MIPS 64KB Flash 8KB RAM Learn More about Microchip Technology microchippic24fj64	Datasheet	178In Stock	$4.64 $4.59 $4.36 $4.33 $3.95	Min.: 1 Mult.: 1	PIC24F	64 kB	8 kB	SPDIP-28	32 MHz	10 bit	21 I/O	2 V	3.6 V	Through Hole	16 bit	- 40 C	+ 85 C	PIC24FJxxGA10x		Tube
16-bit Microcontrollers - MCU 70MIPS, 32KB Flash, 4KB RAM, OpAmps, PTG, 36-pins, up to 125C PIC24EP32GP203-E/M5 Microchip Technology 1: $2.34 359In Stock	Mfr. Part # PIC24EP32GP203-E/M5 Mouser Part # 579-IC24EP32GP203EM5	Microchip Technology	16-bit Microcontrollers - MCU 70MIPS, 32KB Flash, 4KB RAM, OpAmps, PTG, 36-pins, up to 125C Learn More about Microchip Technology microchip dspic33e dscs pic24e mcus	Datasheet	359In Stock	$2.34 $2.13 $1.94	Min.: 1 Mult.: 1	PIC24E	32 kB	4 kB	UQFN-36	60 MHz	10 bit, 12 bit	25 I/O	3 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 125 C	PIC24EPxxxGP20x	AEC-Q100	Tube
16-bit Microcontrollers - MCU 16KB15KB RAM 512B EEPROM PIC24F16KA101-E/MQ Microchip Technology 1: $3.49 381In Stock	Mfr. Part # PIC24F16KA101-E/MQ Mouser Part # 579-PIC24F16KA101EMQ	Microchip Technology	16-bit Microcontrollers - MCU 16KB15KB RAM 512B EEPROM Learn More about Microchip Technology microchip 16bit mcu dsc	Datasheet	381In Stock	$3.49 $3.41 $3.17 $2.89	Min.: 1 Mult.: 1	PIC24F	16 kB	1.5 kB	QFN-20	32 MHz	10 bit	18 I/O	1.8 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 125 C	PIC24FxxKA10x	AEC-Q100	Tube
16-bit Microcontrollers - MCU 16KB 2KBRM 512B EEP 16MIPS 12b ADC CTMU PIC24F16KA301-I/P Microchip Technology 1: $4.11 232In Stock	Mfr. Part # PIC24F16KA301-I/P Mouser Part # 579-PIC24F16KA30-1IP	Microchip Technology	16-bit Microcontrollers - MCU 16KB 2KBRM 512B EEP 16MIPS 12b ADC CTMU Learn More about Microchip Technology microchipPIC24F32KA304	Datasheet	232In Stock	$4.11 $3.77 $3.76 $3.42	Min.: 1 Mult.: 1	PIC24F	16 kB	2 kB	PDIP-20	32 MHz	12 bit	18 I/O	1.8 V	3.6 V	Through Hole	16 bit	- 40 C	+ 85 C	PIC24(L)FxxKA30x	AEC-Q100	Tube
16-bit Microcontrollers - MCU 16B MCU 28LD32KB DMA 40MIPS PIC24HJ32GP302-I/SP Microchip Technology 1: $5.66 276In Stock	Mfr. Part # PIC24HJ32GP302-I/SP Mouser Part # 579-PIC24H32GP302ISP	Microchip Technology	16-bit Microcontrollers - MCU 16B MCU 28LD32KB DMA 40MIPS Learn More about Microchip Technology microchip 16bit mcu dsc	Datasheet	276In Stock	$5.66 $5.19 $4.69	Min.: 1 Mult.: 1	PIC24H	32 kB	4 kB	SPDIP-28	40 MHz	10 bit, 12 bit	21 I/O	3 V	3.6 V	Through Hole	16 bit	- 40 C	+ 85 C	PIC24HJxxGP30x	AEC-Q100	Tube
16-bit Microcontrollers - MCU 16bit MCU w/Crypto 128KB Flash, 8KB RAM PIC24FJ128GB204-E/ML Microchip Technology 1: $5.96 166In Stock	Mfr. Part # PIC24FJ128GB204-E/ML Mouser Part # 579-24FJ128GB204EML	Microchip Technology	16-bit Microcontrollers - MCU 16bit MCU w/Crypto 128KB Flash, 8KB RAM Learn More about Microchip Technology microchip pic24fj	Datasheet	166In Stock	$5.96 $5.95 $5.46 $4.94	Min.: 1 Mult.: 1	PIC24F	128 kB	8 kB	QFN-44	32 MHz	10 bit, 12 bit	34 I/O	2 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 125 C	PIC24FJxxxGB20x		Tube
16-bit Microcontrollers - MCU PIC24F Advanced Analog XLP LCD USB PIC24FJ64GC006-I/MR Microchip Technology 1: $6.25 158In Stock	Mfr. Part # PIC24FJ64GC006-I/MR Mouser Part # 579-PC24FJ64GC006IMR	Microchip Technology	16-bit Microcontrollers - MCU PIC24F Advanced Analog XLP LCD USB Learn More about Microchip Technology microchip pic24fj	Datasheet	158In Stock	$6.25 $5.74 $5.19 $5.18	Min.: 1 Mult.: 1	PIC24F	64 kB	8 kB	QFN-64	32 MHz	12 bit, 16 bit	53 I/O	2 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	PIC24FJxxxGC0xx		Tube
16-bit Microcontrollers - MCU 16KB 2KBRM 512B EE 16MIPS 12b ADC CTMU PIC24F16KA302-E/SS Microchip Technology 1: $4.16 223In Stock	Mfr. Part # PIC24F16KA302-E/SS Mouser Part # 579-PIC24F16KA302ESS	Microchip Technology	16-bit Microcontrollers - MCU 16KB 2KBRM 512B EE 16MIPS 12b ADC CTMU Learn More about Microchip Technology microchipPIC24F32KA304	Datasheet	223In Stock	$4.16 $3.82 $3.47	Min.: 1 Mult.: 1	PIC24F	16 kB	2 kB	SSOP-28	32 MHz	12 bit	24 I/O	1.8 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 125 C	PIC24(L)FxxKA30x	AEC-Q100	Tube
16-bit Microcontrollers - MCU 128KB FL 8Kb RAM 53I/O PIC24FJ128GA006-I/MR Microchip Technology 1: $4.96 160In Stock	Mfr. Part # PIC24FJ128GA006-I/MR Mouser Part # 579-24FJ128GA006IMR	Microchip Technology	16-bit Microcontrollers - MCU 128KB FL 8Kb RAM 53I/O Learn More about Microchip Technology microchip pic24fj	Datasheet	160In Stock	$4.96 $4.56 $4.55	Min.: 1 Mult.: 1	PIC24F	128 kB	8 kB	QFN-64	32 MHz	10 bit	53 I/O	2 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	PIC24FJxxxGA006		Tube
16-bit Microcontrollers - MCU MCU 3/5V 32K+2K I-temp 32-LQFP Renesas Electronics R5F21276SDFP#V2 R5F21276SDFP#V2 Renesas Electronics 1: $13.15 21In Stock	Mfr. Part # R5F21276SDFP#V2 Mouser Part # 968-R5F21276SDFP#V2	Renesas Electronics	16-bit Microcontrollers - MCU MCU 3/5V 32K+2K I-temp 32-LQFP	Datasheet	21In Stock	$13.15 $10.69 $10.19 $8.85 View $7.63 $7.57 $7.35 Quote	Min.: 1 Mult.: 1														R8C/27		Tray
16-bit Microcontrollers - MCU 16-Bit, RISC, Microcontroller-Based, Ult MAXQ7667AACM/V+ Analog Devices / Maxim Integrated 1: $32.38 38In Stock	Mfr. Part # MAXQ7667AACM/V+ Mouser Part # 700-MAXQ7667AACM/V	Analog Devices / Maxim Integrated	16-bit Microcontrollers - MCU 16-Bit, RISC, Microcontroller-Based, Ult	Datasheet	38In Stock	$32.38 $27.51 $24.85 $23.97 View $22.94 Quote	Min.: 1 Mult.: 1	RISC	32 kB	4 kB	LQFP-48	16 MHz	12 bit	16 I/O	2.5 V	2.5 V	SMD/SMT	16 bit	- 40 C	+ 125 C	MAXQ7667	AEC-Q100	Tray
16-bit Microcontrollers - MCU 8kB Flash 256B RAM 1 0bit ADC + 1 USART A 595-430F1232IRHBR MSP430F1232IRHBT Texas Instruments 1: $9.05 170In Stock	Mfr. Part # MSP430F1232IRHBT Mouser Part # 595-430F1232IRHBT	Texas Instruments	16-bit Microcontrollers - MCU 8kB Flash 256B RAM 1 0bit ADC + 1 USART A 595-430F1232IRHBR Learn More about Texas Instruments ti msp430 mcus	Datasheet	170In Stock	Cut Tape $9.05 $7.02 $6.21 $5.96 Reel $5.39 View $5.36 Quote MouseReel Available	Min.: 1 Mult.: 1 : 250	MSP430	8 kB	256 B	VQFN-32	8 MHz	10 bit	22 I/O	1.8 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	MSP430F1232		Reel, Cut Tape, MouseReel
16-bit Microcontrollers - MCU 24 MHz 105 C integra ted analog microcon A 595-MSP430FR2353TDBT MSP430FR2353TDBTR Texas Instruments 1: $5.89 404In Stock	Mfr. Part # MSP430FR2353TDBTR Mouser Part # 595-430FR2353TDBTR	Texas Instruments	16-bit Microcontrollers - MCU 24 MHz 105 C integra ted analog microcon A 595-MSP430FR2353TDBT Learn More about Texas Instruments ti msp430fr215 msp430fr235 mcus	Datasheet	404In Stock	Cut Tape $5.89 $4.05 $3.77 $3.32 View Reel $2.19 $3.15 $2.82 $2.59 $2.19 MouseReel Available	Min.: 1 Mult.: 1 : 2,000	MSP430	16 kB	2 kB	TSSOP-38	24 MHz	12 bit	34 I/O	1.8 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 105 C	MSP430FR2353		Reel, Cut Tape, MouseReel
16-bit Microcontrollers - MCU Mixed Signal MCU A 5 95-MSP430F5507IRGZR A 595-MSP430F5507IRGZR MSP430F5507IRGZT Texas Instruments 1: $7.59 187In Stock	Mfr. Part # MSP430F5507IRGZT Mouser Part # 595-MSP430F5507IRGZT	Texas Instruments	16-bit Microcontrollers - MCU Mixed Signal MCU A 5 95-MSP430F5507IRGZR A 595-MSP430F5507IRGZR Learn More about Texas Instruments ti msp430 mcus	Datasheet	187In Stock	Cut Tape $7.59 $5.86 $5.16 $4.95 Reel $4.71 View $4.49 $4.47 $4.42 Quote MouseReel Available	Min.: 1 Mult.: 1 : 250	MSP430	32 kB	4 kB	VQFN-48	25 MHz	10 bit	31 I/O	1.8 V	3.6 V	SMD/SMT	16 bit	- 40 C	+ 85 C	MSP430F5507		Reel, Cut Tape, MouseReel